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UF IDDynamics
University of Florida research group studying infectious disease dynamics. Based in Department of Biology and Emerging Pathogens Institute.
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UF IDDynamics retweeted
Matt Hitchings Sep 20
UF COVID update 20th September (viz via ). Daily total and positive tests as reported on dashboard (some testing/reporting delay). Line is 7-day rolling average. 1/4
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UF IDDynamics retweeted
Pejman Rohani Sep 2
Who could have seen this coming?
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UF IDDynamics retweeted
Jeff Huber 🇺🇸 Aug 22
U of Illinois did 1.3% of total testing done in the US last week – w/ a low-cost saliva-based test they developed to test 50K students & faculty, 2x/wk, with <6 hr turnaround. Is this science fiction? 👉No. They had the will to try. What's your school doing?
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Emerging Pathogens Jul 23
A new study published today in PLOS-Pathogens deepens our understanding of how past exposures to flu affect our body’s response to new or currently circulating strains and seasonal flu vaccines:
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Gregg Gonsalves Jul 19
Replying to @gregggonsalves
Americans are looking for some sort of permission slip from scientists to get out of doing the work we need to do RIGHT NOW to ever have any chance of re-opening safely (and I fear it's too late for the fall). 2/
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UF IDDynamics retweeted
Gregg Gonsalves Jul 19
So, there is something strange going on in America, I keep getting asked "can we reopen schools," "what's going to happen with universities, my son is starting at..." No one asks WHAT WILL IT TAKE TO RE-OPEN THEM. 1/
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UF IDDynamics retweeted
Samuel V. Scarpino #BlackLivesMatter Jun 24
I am calling on tenured faculty across academia to use their status, stand up to the universities, and protect graduate students/adjuncts/postdocs/non-tenured faculty/staff/contract workers/other vulnerable individuals at universities.
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Anne Applebaum Jun 4
In the past 24 hours, several senior American generals have spoken out to remind Americans that they serve the constitution, not the president. Where are the senior Republicans? Why don't they offer a similar message? Here is my explanation:
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UF IDDynamics retweeted
Samuel V. Scarpino #BlackLivesMatter May 4
Mean number of days between someone getting infected with and their *infector* showing symptoms is negative 0.19 days! Suggesting most transmission is happening from pre-symptomatic individuals and masks are critical.
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UF IDDynamics retweeted
Joseph Lewnard Apr 29
Thrilled to see this work now out in . We find that pneumococcal conjugate vaccines and rotavirus vaccines reduce antibiotic use among children in low and middle income countries: . 1/n
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Laurie Garrett Apr 18
As politicians yammer abt "herd immunity" , vaccines, antibody tests & other immune syst issues that can make or break policies, a LOT is unknown, mysterious, and confusing. So here's the best summary so far of immune resps to
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UF IDDynamics Apr 18
Replying to @uf_idd
Conclusions: many of questions still unanswered for , but big implications for testing and deployment of therapeutics, vaccines, and non-pharmaceutical interventions. Other CoVs represent our “best guess” at immune responses to SARS-CoV-2 8/8
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UF IDDynamics Apr 18
Replying to @uf_idd
Population seroprevalence: serosurveys for endemic CoVs show that most people get infected with multiple strains in childhood but adults still get CoV infections – evidence that lifelong, complete immunity not acquired. Key gap: immunity to SARS-CoV-2 may be different 7/8
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UF IDDynamics Apr 18
Replying to @uf_idd
Immunopathogenesis: many proposed mechanisms for how immune reaction to infection can cause damage. Key gap: no strong causal evidence yet for antibody-dependent enhancement (ADE). However, vaccines and therapeutics have to address this risk 6/8
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UF IDDynamics Apr 18
Replying to @uf_idd
Cross-reactivity: within Alpha- and Beta-CoVs but minimal between groups. SARS and MERS elicit antibody responses to endemic CoVs, but not vice versa. This is good news for assay development. Key gap: no evidence on cross-protection 5/8
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UF IDDynamics Apr 18
Replying to @uf_idd
Correlates of protection: human challenge studies show that some levels of serum IgG, IgA, neut, mucosal IgA protective against infection and disease. However, challenge studies show re-infection with same strain possible in 1 year. Key gap: lack of evidence for SARS and MERS 4/8
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UF IDDynamics Apr 18
Replying to @uf_idd
Antibody responses and severity: antibody kinetics varied among illnesses of different severity with longer duration of detectable antibody associated with more severe symptoms. Key gap: will mild cases of SARS-CoV-2 have detectable serum responses? 3/8
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UF IDDynamics Apr 18
Replying to @uf_idd
Antibody kinetics after infection: time to detection is similar for SARS and SARS-CoV-2 (11-12 days), and longer for MERS (16 days). IgG wanes over time but has been detected up to three years following infection. Key gap: studies of asymptomatic/mild infections 2/8
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UF IDDynamics Apr 18
Our systematic of antibody-mediated is out as a pre-print. . Short thread on the main questions and findings from the literature on endemic coronaviruses, MERS, and SARS 1/8
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Emerging Pathogens Mar 10
. and EPI biology professor investigates outbreak dynamics of emerging respiratory viral infections. He helped produce early estimates for the COVID-19 outbreak in China, as well as past SARS and MERS outbreaks:
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