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Simon Myers
@simon_r_myers
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12. stu |
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++1 for Zcow-pow (one). No-one can ever remember the gene name, and this might rescue us!
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Simon Myers
@simon_r_myers
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12. stu |
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PS I set the "chromosome-wide" version of this question (for a sample of size n) as an Oxford finals problem in 2017!
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Simon Myers
@simon_r_myers
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12. stu |
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However the bound increases so quickly with recombination rate it essentially gives infinite time (many chunks coinciding in the same individual is really unlikely), for a whole chromosome.
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Simon Myers
@simon_r_myers
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12. stu |
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+1 for Griffiths and Marjoram '97, which has I think the formula for the "grand TMRCA" of a sample. I think that's the first individual ancestral to a whole stretch of DNA.
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Simon Myers
@simon_r_myers
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8. stu |
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Another ZCWPW1 paper doi.org/10.1101/836023, here from the Liu group, has hit biorXiv! That makes 3 in the last fortnight, with our preprint doi.org/10.1101/821678 and the @todd_macfarlan preprint
doi.org/10.1101/821603. Hopefully this gene is feeling properly loved at last.
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| Simon Myers proslijedio/la je tweet | ||
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Jerome Kelleher
@jeromekelleher
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1. stu |
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Summary of Relate and tsinfer in @naturemethods this month: nature.com/articles/s4159…
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Simon Myers
@simon_r_myers
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30. lis |
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I have come to love it! After all, it's number 1, among all (both) the ZCWPW genes.
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Todd Macfarlan
@todd_macfarlan
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29. lis |
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Our new preprint on the co-evolution of a dual histone methyltransferase (PRDM9) and it’s reader (ZCWPW1) that controls recombination patterns in vertebrates is out. Great collaboration with Nussenzweig and Cheng labs. Congrats to Mohamed and Jacob! biorxiv.org/content/10.110…
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Simon Myers
@simon_r_myers
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30. lis |
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Our new paper on ZCWPW1, now on bioRxiv! biorxiv.org/cgi/content/sh… twitter.com/DanielJohnWell…
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| Simon Myers proslijedio/la je tweet | ||
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Kelley Harris
@Kelley__Harris
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2. ruj |
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Congratulations to @jeromekelleher, @gil_mcvean, @leo_speidel, and @simon_r_myers on publishing their fabulous new methods for inferring genealogical trees from whole genomes! Here's my take on why these papers make it a great day for population genetics:
nature.com/articles/s4158…
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| Simon Myers proslijedio/la je tweet | ||
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Leo Speidel
@leo_speidel
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2. ruj |
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And here is an openly viewable version of the paper rdcu.be/bP6Iu
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| Simon Myers proslijedio/la je tweet | ||
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Dr Yan Wong
@DrYanWong
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2. ruj |
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Our "Ancestry of Everyone" paper is finally out! nature.com/articles/s4158… . Hopefully a major salvo in the upcoming population genetics revolution.
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| Simon Myers proslijedio/la je tweet | ||
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Wilder Wohns
@WilderWohns
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2. ruj |
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Remaking genetics one inferred tree (sequence) at a time... Was such a pleasure to be involved in this project! twitter.com/DrYanWong/stat…
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| Simon Myers proslijedio/la je tweet | ||
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Leo Speidel
@leo_speidel
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2. ruj |
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Also, we deposited our 1000G allele ages, selection p-values, and population sizes here: zenodo.org/record/3234689
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| Simon Myers proslijedio/la je tweet | ||
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Leo Speidel
@leo_speidel
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2. ruj |
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Thanks @Kelley__Harris for the really nice news and views piece!
nature.com/articles/s4158…
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| Simon Myers proslijedio/la je tweet | ||
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Leo Speidel
@leo_speidel
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2. ruj |
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Excited to see our Relate paper for genealogy estimation out today, alongside @jeromekelleher et al’s tsinfer paper!
nature.com/articles/s4158…
Thanks @simon_r_myers, this has been (and still is) a really fun project!
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| Simon Myers proslijedio/la je tweet | ||
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Simon Myers
@simon_r_myers
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2. ruj |
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Our paper on building genealogical trees for thousands of samples is out in Nature Genetics today, with excellent N+V by @Kelley__Harris! Congratulations also @jeromekelleher on your paper. nature.com/articles/s4158…
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Simon Myers
@simon_r_myers
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2. ruj |
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Our paper on building genealogical trees for thousands of samples is out in Nature Genetics today, with excellent N+V by @Kelley__Harris! Congratulations also @jeromekelleher on your paper. nature.com/articles/s4158…
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| Simon Myers proslijedio/la je tweet | ||
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Nicolas Altemose
@NAltemose
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29. kol |
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The reviews are in! "a tour de force", "a unique & exciting work", "a valuable resource for the community". After constructive review, our paper is out 🥳 w/ my co-1sts @OxfordRan @Emmanuellebito1 & PI @simon_r_myers at @UniofOxford in @NatureComms: nature.com/articles/s4146… /1
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Simon Myers
@simon_r_myers
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29. kol |
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Our paper investigating the interplay between genetic variation and recombination in mammals is out today in Nature Comms! Congratulations @NAltemose @OxfordRan @Emmanuellebito1!
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