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Peter Park
@
ParkLabGenomics
Boston, MA
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bioinformatics and genomics, applications to cancer and neuroscience
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Tweetovi
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27
Pratim
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377
Osobe koje vas prate
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Peter Park
@ParkLabGenomics
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1. velj |
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Connor Horton wrote his undergraduate senior thesis in my lab and just published part of it as this paper. Superb work, Connor! GiniQC: a measure for quantifying noise in single-cell Hi-C data academic.oup.com/bioinformatics…
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Peter Park
@ParkLabGenomics
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1. velj |
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Max @msherman997 (formerly with my lab, now with Po-Ru Loh) applies haplotype phasing to genotyping data from >10K autism cases to identify mosaic copy number variants! He also found two mosaic CNVs in brain WGS data
medrxiv.org/content/10.110…
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Harvard OTD
@HarvardTechXfer
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30. sij |
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Tomorrow! (Friday) come down to @labcentral for our latest Guppy Tank event, featuring innovations from George Church's lab and Peter Park's lab at @harvardmed. RSVP: otd.harvard.edu/events/guppy-t… @ParkLabGenomics @geochurch
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Peter Park
@ParkLabGenomics
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30. sij |
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My department @dbmi just opened a search for a junior faculty member with interest in applying machine learning to the diagnosis and treatment of disease, broadly defined. More information: academicpositions.harvard.edu/postings/9553
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Peter Park
@ParkLabGenomics
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6. sij |
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Here is the flowchart of the algorithm. It is intuitively clear that algorithms that incorporate more features at the read-level should perform better (as some recent algorithms do); the hard part was coming up with enough true positives to train the classifier. pic.twitter.com/cCbl8lWV11
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Peter Park
@ParkLabGenomics
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6. sij |
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Yanmei's paper is out today. MosaicForecast uses 30+ read-level features (+ML) to identify mosaic mutations in normal cells, where the variant allele fraction is << what you typically see in cancer cells. A key innovation is to use haplotype phasing to generate a training set. twitter.com/NatureBiotech/…
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Peter Park
@ParkLabGenomics
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12. pro |
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Multiple postdoc positions available in the lab! See careers.iscb.org/jobs/view/7005 A great deal of independence (if desired), a lot of exciting projects in cancer genomics/neurogenetics--single cell WGS, mutational signatures, CRUK Grand Challenge, antisense oligo therapeutics, etc
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Peter Park
@ParkLabGenomics
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12. pro |
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Jake presents his work from his recent Cell paper at this lung cancer meeting and wins the Grand Prize (10K)! twitter.com/EGFRSummit/sta…
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| Peter Park proslijedio/la je tweet | ||
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4DN DCIC
@4dn_dcic
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7. pro |
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We're inspired by all the great talks at the #4DNucleome annual meeting this year & excited for phase 2! Reach out to us at support@4dnucleome.org to submit your recent data!
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Peter Park
@ParkLabGenomics
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9. lis |
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2/2 This article tells the story of discovering a transposon insertion (from whole-genome sequencing) that caused a splicing defect in CLN7, developing an antisense oligonucleotide drug, and the therapy resulting in reduction in seizures--all in <1 yr. nejm.org/doi/full/10.10…
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Peter Park
@ParkLabGenomics
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9. lis |
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1/2 Just out: "Timely Development of a Mutation-Specific Drug", with an accompanying editorial, on the front page of NEJM. Congrats to the lead author Jinkuk Kim (a postdoc in the lab), who worked with our collaborator @timyu on this amazing story. pic.twitter.com/EDm1ZbUycr
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Peter Park
@ParkLabGenomics
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8. lis |
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It was wonderful to discuss some of the challenges we face in data analysis with the many thoughtful editors at the Cell Press office in Cambridge! twitter.com/biologyfan/sta…
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Peter Park
@ParkLabGenomics
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12. ruj |
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It's wonderful to welcome 12 accomplished students to our Bioinformatics & Integrative PhD program this fall! pic.twitter.com/Mk6mqoKuga
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Peter Park
@ParkLabGenomics
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11. ruj |
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A lab outing to the Boston Harbor Islands last week! pic.twitter.com/XmwiDMIQFo
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Peter Park
@ParkLabGenomics
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29. kol |
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Joe's SCAN-SNV (Single Cell ANalysis of SNVs) paper is out. To deal with allelic imbalance, Joe determines whether a candidate SNV is a FP based on the allelic imbalance at nearby SNPs. Interestingly, he finds that a "single cell" in a Nat Methods paper is actually a doublet! twitter.com/NatureComms/st…
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Peter Park
@ParkLabGenomics
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29. kol |
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We're excited to see Isidro, a Park lab alum, start his own group at EMBL-EBI. He is a terrific computational scientist, a generous colleague, and a wonderful collaborator--we'll miss you in Boston, Isidro! twitter.com/emblebi/status…
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Peter Park
@ParkLabGenomics
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16. kol |
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Analyzing allelic fractions of SNVs as molecular clocks while accounting for CNVs and SVs, Lixing has painstakingly constructed evolutionary history of tumors from bulk WGS data. twitter.com/GenomeBiology/…
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Peter Park
@ParkLabGenomics
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15. srp |
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Boston in the summer pic.twitter.com/LEUBNczOnP
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| Peter Park proslijedio/la je tweet | ||
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🅽🅸🅻🆂 🅶🅴🅷🅻🅴🅽🅱🅾🆁🅶
@ngehlenborg
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19. lip |
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Congratulations to my @HarvardDBMI colleague @KharchenkoLab on being installed as the inaugural Gilbert S Omenn MD ‘65, PhD Associate Professor of Biomedical Informatics @harvardmed. Well deserved and well done, Peter! pic.twitter.com/R2J08mRdV4
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Peter Park
@ParkLabGenomics
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20. lip |
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Congrats to Peter K (@KharchenkoLab)! It was a privilege to have him as a postdoc in my lab, and I relished the opportunities to speak about his science and his many other talents at the ceremony! twitter.com/zakkohane/stat…
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