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David A. Markowitz
IARPA Program Manager. Views are my own.
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David A. Markowitz 14 h
In case anyone would enjoy a 30 minute video update on the program and some of the exciting things we're learning from cortical connectomes, here's my briefing to NIH BRAIN leadership last week. Starting at 43:15:
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E. Le Moal 1. velj
Unpicking the proteome in single cells Fantastic perspective by in .
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David A. Markowitz 31. sij
Odgovor korisniku/ci @bingbrunton @mferr133
This is just Markowitz portfolio theory applied to program management. Diversify across assets to maximize expected return!
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David A. Markowitz 31. sij
Odgovor korisniku/ci @mferr133
Just to be clear, this is in addition to my existing portfolio of computational neuroscience, DNA storage, and robotics programs.
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David A. Markowitz 31. sij
Some professional news: as of last week, I run USG's ongoing biosecurity program focused on detecting engineered biological systems that have been accidentally or deliberately released into the world. What a week for it, too.
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Ilana Witten 29. sij
Pls RT: Do you like systems neuro, technical management & collaborative science? We're hiring a scientific/technical manager for - apply here Goldman Tank
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David A. Markowitz 25. sij
Odgovor korisniku/ci @slavovLab
Exactly. Much like genomics, we will need to generate and compare data from many individuals before we can really begin to understand how structure relates to function. Arguments against scaling up methods to support this because we haven't yet gained that understanding are weak.
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David A. Markowitz 25. sij
Odgovor korisniku/ci @slavovLab
How much can we learn from a single person's genome?
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David A. Markowitz 25. sij
Odgovor korisniku/ci @neurowitz
It really feels like we're seeing exponential growth in the imaging and reconstruction rates for EM data sets.
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David A. Markowitz 25. sij
Odgovor korisniku/ci @neurowitz
Jeff Lichtman's group has also successfully sectioned and imaged mm-scale tissue volumes, using multiSEM (vs TEMCA at Allen Institute). I've now seen two mm-scale datasets from mouse cortex and two from human cortex acquired using these different pipelines. Wow.
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David A. Markowitz 25. sij
Odgovor korisniku/ci @AllenInstitute @darbly
In parallel with their above work, and collabs have scaled up sectioning and imaging tools to acquire multi-petabyte datasets spanning millimeter-scale tissue volumes.
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David A. Markowitz 25. sij
Odgovor korisniku/ci @neurowitz
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David A. Markowitz 25. sij
Odgovor korisniku/ci @neurowitz
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David A. Markowitz 25. sij
Odgovor korisniku/ci @neurowitz
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David A. Markowitz 25. sij
Odgovor korisniku/ci @neurowitz
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David A. Markowitz 25. sij
Odgovor korisniku/ci @neurowitz
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David A. Markowitz 25. sij
What an exciting couple of months for the field of connectomics! Thought it would be good to post a thread that captures recent progress--
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David A. Markowitz 22. sij
Odgovor korisniku/ci @csdashm @AdrianAWanner
An alternative viewpoint is that raw data and discovery tools, absent scientific claims, should not need to undergo peer review. I don't share that view, but it should be acknowledged.
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David A. Markowitz 22. sij
Odgovor korisniku/ci @csdashm @AdrianAWanner
I have tremendous respect for this team's scientific achievements. I just don't understand what was so urgent about getting popular media coverage that they couldn't wait to put their work through peer review before calling the press.
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David A. Markowitz 22. sij
Odgovor korisniku/ci @csdashm @AdrianAWanner
As expected, the deluge of popular press coverage timed to coincide with the release of this preprint is billing it as a publication.
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