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David A. Markowitz
@
neurowitz
Boston, MA and Washington, DC
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IARPA Program Manager. Views are my own.
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1.127
Tweetovi
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155
Pratim
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1.032
Osobe koje vas prate
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David A. Markowitz
@neurowitz
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14 h |
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In case anyone would enjoy a 30 minute video update on the @IARPAnews #MICrONS program and some of the exciting things we're learning from cortical connectomes, here's my briefing to NIH BRAIN leadership last week. Starting at 43:15: videocast.nih.gov/summary.asp?li…
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E. Le Moal
@ELM_ELM_ELM_ELM
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1. velj |
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Unpicking the proteome in single cells science.sciencemag.org/content/367/64… Fantastic perspective by @slavovLab in @sciencemagazine.
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David A. Markowitz
@neurowitz
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31. sij |
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This is just Markowitz portfolio theory applied to program management. Diversify across assets to maximize expected return!
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David A. Markowitz
@neurowitz
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31. sij |
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Just to be clear, this is in addition to my existing portfolio of computational neuroscience, DNA storage, and robotics programs.
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David A. Markowitz
@neurowitz
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31. sij |
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Some professional news: as of last week, I run USG's ongoing biosecurity program focused on detecting engineered biological systems that have been accidentally or deliberately released into the world. What a week for it, too. iarpa.gov/index.php/rese…
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Ilana Witten
@IlanaWitten
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29. sij |
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Pls RT: Do you like systems neuro, technical management & collaborative science? We're hiring a scientific/technical manager for braincogs.org - apply here tiny.cc/jk6bjz
@PrincetonNeuro @brody_lab @SebastianSeung @SamWangPhD @jpillowtime Goldman Tank
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David A. Markowitz
@neurowitz
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25. sij |
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Exactly. Much like genomics, we will need to generate and compare data from many individuals before we can really begin to understand how structure relates to function. Arguments against scaling up methods to support this because we haven't yet gained that understanding are weak.
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David A. Markowitz
@neurowitz
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25. sij |
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How much can we learn from a single person's genome?
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David A. Markowitz
@neurowitz
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25. sij |
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It really feels like we're seeing exponential growth in the imaging and reconstruction rates for EM data sets.
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David A. Markowitz
@neurowitz
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25. sij |
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Jeff Lichtman's group has also successfully sectioned and imaged mm-scale tissue volumes, using multiSEM (vs TEMCA at Allen Institute). I've now seen two mm-scale datasets from mouse cortex and two from human cortex acquired using these different pipelines. Wow.
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David A. Markowitz
@neurowitz
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25. sij |
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In parallel with their above work, @AllenInstitute @darbly and collabs have scaled up sectioning and imaging tools to acquire multi-petabyte datasets spanning millimeter-scale tissue volumes. biorxiv.org/content/10.110…
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David A. Markowitz
@neurowitz
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25. sij |
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David A. Markowitz
@neurowitz
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25. sij |
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David A. Markowitz
@neurowitz
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25. sij |
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David A. Markowitz
@neurowitz
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25. sij |
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David A. Markowitz
@neurowitz
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25. sij |
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David A. Markowitz
@neurowitz
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25. sij |
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What an exciting couple of months for the field of connectomics! Thought it would be good to post a thread that captures recent progress--
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David A. Markowitz
@neurowitz
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22. sij |
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An alternative viewpoint is that raw data and discovery tools, absent scientific claims, should not need to undergo peer review. I don't share that view, but it should be acknowledged.
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David A. Markowitz
@neurowitz
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22. sij |
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I have tremendous respect for this team's scientific achievements. I just don't understand what was so urgent about getting popular media coverage that they couldn't wait to put their work through peer review before calling the press.
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David A. Markowitz
@neurowitz
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22. sij |
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As expected, the deluge of popular press coverage timed to coincide with the release of this preprint is billing it as a publication. twitter.com/verge/status/1…
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