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Patrick Reilly
Evolutionary Genomics of Lepidoptera, de novo Assembly Aficionado, grad student in 's lab, Tweets are my own.
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Patrick Reilly 15. stu
Such a cool finding spearheaded by and : How is gene expression matched between the sexes on the sex chrom? In flies, X is ⬆️ in males; in worms and silk moth, X is ⬇️ in the XX or ZZ sex. The Monarch neo-Z fusion shows **both**: anc-Z ⬇️ in ZZ, neo-Z ⬆️ in ZW!
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Patrick Reilly 31. lis
Congrats Dr. ! Lab won't be the same without you; the Stern lab will be lucky to have you!
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Patrick Reilly 21. lip
Odgovor korisniku/ci @nuclearkatie
Vermont Yankee, assuming “decommissioned” includes those currently in the process. Your tweets were a helpful reminder of the travesty that was the grossly misinformed vote to revoke its permit.
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Patrick Reilly 12. lip
Amusement for the day: MooSciTIC () is a great acronym, quite relevant for West African research. For the non-Francophones, moustique=mosquito.
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Patrick Reilly 10. svi
Odgovor korisniku/ci @tangming2005
Rough method: If no reference genome (presumably since transgene), de novo assemble with Trinity, then map CDS sequence onto Trinity contigs with e.g. exonerate, GMAP, BLAST, etc. Small scale simple version of what PASA and MAKER do for whole genomes, if I recall correctly.
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Patrick Reilly 6. svi
Odgovor korisniku/ci @DarkestWishesM @peergoon i 2 ostali
Ash is correct, testosterone (and the other androgens) are members of the same steroidogenesis biochemical pathway as estradiol (and the other estrogens) — both males and females have measurable levels of both, though differing in equilibrium. Her “fat” analogy is on point.
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Patrick Reilly 30. tra
Cool work come to fruition! Glad to see those grueling months of CRISPR and crosses paying off for and !
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Patrick Reilly 6. tra
Odgovor korisniku/ci @rmp033 @evolscientist
As somewhat expected of Hi-C, just be careful trusting some SALSA2 joins. It made a single giant scaffold out of the major arms of Drosophila teissieri regardless of MQ filters, had to manually split to fix. (HiCembler made too few joins, and 3d-dna jumbled everything.)
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Patrick Reilly 23. velj
Odgovor korisniku/ci @KMS_Meltzy
Seeing all these mentions of TSVs instead reminds me of the oft-forgotten 1E and 1F non-printing ASCII delimiters. Poor orphaned characters that could avoid so much parsing pain :(
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Patrick Reilly 19. velj
A good friend of mine suffers from epilepsy, and she is working to promote awareness through - 3.4 million people in the US suffer from active epilepsy. It's hard to learn when you could have a seizure at any time, let alone teachers not believing you have epilepsy.
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Patrick Reilly 16. sij 2019.
So true! Beyond that, due to some confusion about parenthetical terminology when talking code (especially crazy awk one-liners) in the lab, we now call ( banana, [ staple, and { coat hangar. Bonus is when you get to say “You’re missing a coat hangar”
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Patrick Reilly 13. sij 2019.
Odgovor korisniku/ci @kbradnam
Of course the BLAST citation is just a mis-citation of Gapless BLAST. (I’m guilty of that mistake too)
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Patrick Reilly 11. sij 2019.
Odgovor korisniku/ci @biomonika
Maybe not super kosher with some sysadmins for some clusters, but I regularly nohup in background for stuff like that. That way you still get notified of the exit code, and judicious use of /usr/bin/time -v with > and 2> gives you runtime and errors.
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Patrick Reilly proslijedio/la je tweet
Ed Yong 5. sij 2019.
This piece on millennial burnout is definitive. It surpasses what has come before and sets a *very* high benchmark for anything on this topic to follow. It's profound, sweeping, and breathtakingly good. I'm going to read it again.
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Patrick Reilly 4. sij 2019.
Odgovor korisniku/ci @macmanes @sjackman i 2 ostali
Had seen this preprint recently, but it relies on SSPACE-LR output (to ID reads relevant to a gap), so a bit limited applicability:
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Patrick Reilly 16. pro 2018.
Odgovor korisniku/ci @vagar112
Same, and view the replacement awk one-liners with pride 😂
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Patrick Reilly 2. pro 2018.
Odgovor korisniku/ci @ChanchalYV @rmwaterhouse i 3 ostali
Though developed with PB and Illumina data, you might want to try DBG2OLC (using Illumina contigs from Platanus)
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Patrick Reilly 25. stu 2018.
Odgovor korisniku/ci @biolojical @MTdellarte
That awkward moment when you want to add 🦋, but realize the karyotypic diversity... 42, 54, 56, 60, 60, 60, 62 (Hmel, Bman, Bmor, Dple, Pgla, Pxut, Mcin), and that’s just from assemblies. Cytogenetics gets em out to 240+
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Patrick Reilly 17. ožu 2018.
Odgovor korisniku/ci @sinobug @FascinatingPupa
That caudal horn though!
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Patrick Reilly proslijedio/la je tweet
Mental Health Notes™ 📄 21. sij 2018.
depression symptoms ⚠️ • loss of interest in things you liked. • insomnia. • feelings of guilt and worthlessness. • overeating or appetite loss. • trouble concentrating. • persistent sad or “empty” feelings. • suicidal thoughts Will you RT for depression awareness?
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