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Jeffrey Flier
Let’s be clear. Experts on epigenetics I’ve spoken w are extremely skeptical about causal link between epigenetic marks that correlate w chronological age and the aging process, such that aging could be reversed. Look for the scientific literature, not for answers.
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Paul Summergrad 26. lis
Odgovor korisniku/ci @jflier @WSJopinion
How secure do you think the emerging literature is on the multigenerational inheritance of environmentally mediated events or characteristics ?
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Jeffrey Flier 26. lis
Odgovor korisniku/ci @paulsummergrad @WSJopinion
Hard to say- there are so many reports, with widely varying methods and claims. I suspect some of it is right, lots not.
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Michael Joyner 26. lis
Odgovor korisniku/ci @jflier @WSJopinion
So many fountains of youth so little time...... WSJ should not be doing infomercials
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halvorz 26. lis
Odgovor korisniku/ci @jflier @WSJopinion
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hypercoagulable 27. lis
Odgovor korisniku/ci @jflier @WSJopinion
Funny that you would make an appeal to authority to arguably the biggest authority in the field. Half the scientific literature you refer to came from his team.
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Karsten Suhre 27. lis
Odgovor korisniku/ci @jflier @minouye271 @WSJopinion
Agree - age associated methylation marks likely are readouts for gene expression- and as such non causal markers - modifying methylation back to a “younger” state might even do harm, as it reverses what the body might need when it ages.
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Adam Ashwal 27. lis
Odgovor korisniku/ci @jflier @WSJopinion
Do you have a recommendation of something to read in this vein? I don't really understand the criticism as you've formulated it. Acetylation, either by programming or entropy, leading to aging phenotypes seems well supported?
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linhdtu 26. lis
Odgovor korisniku/ci @jflier @WSJopinion
guy is talking his book and has plenty of conflict of interest. One thing i learn from l'affaire WeWork is that being super duper optimistic abt future usually pays off handsomely. One needs to be real lucky to rake off 1B$ like Adam Neumann but otherwise than that it still pays
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Prakash Hande 26. lis
Odgovor korisniku/ci @jflier @WSJopinion
Obsession is another thing! Most of us are obsessed with our research - we believe that only “our” research will cure disaeases Or other conditions!
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