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Sam Finlayson
MD-PhD Candidate, working on machine learning for (bio)medicine at + . Past: (BA, MS)
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Sam Finlayson 12 h
Odgovor korisniku/ci @JFutoma
might be the closest yet?
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Sam Finlayson 12 h
Odgovor korisniku/ci @DrLukeOR @tberzin i 3 ostali
To be clear: I don't mean this is a "gotcha," as I see the authors even pointed this out themselves on the other thread. It's a cool study and it's exciting to see AI enter the sham-controlled phase. Great progress.
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Sam Finlayson 12 h
Odgovor korisniku/ci @DrLukeOR @tberzin i 3 ostali
Great point, and I'm definitely not criticizing the authors for not doing the prohibitively expensive. That said, I still don't think we can say we've had our first proven case of AI benefiting patients yet. No outcome counterfactual for (small) otherwise missed lesions.
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Scott Gottlieb, MD 17 h
Thread: There are now 2 deaths in 146 patients diagnosed with outside China. It’s a case fatality rate of 1.37%. This may be our best estimate to date. The patients include mild disease as well those presenting with pneumonia. It tracks with 2% CFR reported in China.
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Sam Finlayson 20 h
Odgovor korisniku/ci @tberzin @EricTopol i 2 ostali
Yep, I immediately regretted saying "clinical" endpoint rather than "clinical outcome." Sorry
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Sam Finlayson 20 h
Odgovor korisniku/ci @tberzin @LancetGastroHep i 3 ostali
Congrats to the team on a nice paper! And good thread describing it.
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Sam Finlayson 20 h
Cool, thanks for applying. Checks the double-blind box (great!) but endpoint is not a clinical one, correct? AI for endoscopy/colonoscopy is an interesting problem area in general, bc there is usually/often a procedural element baked into the scoping session.
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Tyler Berzin MD, FASGE 22 h
1/9 Quick synopsis of our recent double-blind randomized study on computer-aided polyp detection in , which can be found here:
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Sam Finlayson 21 h
Interesting (and painful) breakdown of what likely happened in Iowa last night. Also, I don't know who came up with the name for "Shadow, Inc." but that's almost a self-parody-level naming move on the part of a contractor building an election tallying tool.
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Derek Lowe 23 h
More disputes on AI-style drug discovery, and hopes that the field can eventually get past this phase:
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Saige Rutherford 24 h
Definitely going to use this feature for my next talk!
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Jeremy Howard 23 h
How did I not know of this until now?
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Sam Finlayson 24 h
Odgovor korisniku/ci @sTeamTraen @venkmurthy i 3 ostali
This is a perfectly reasonable concern w.r.t. optics. I was just making clear that Venky’s concerns about dichotomania etc were more about one instantiation of the lottery idea than the randomization principle itself. Yours is much more fundamental.
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Sam Finlayson 4. velj
Odgovor korisniku/ci @venkmurthy @mikejohansenmd i 3 ostali
How about scoring all grants but then converting those directly into sampling probabilities? You could use a smooth function that strongly favors the upper quartile, but doesn’t create dichotomania. Then sample over the full range with those probs.
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hardmaru 4. velj
A pneumonia outbreak associated with a new coronavirus of probable bat origin (This is an unedited manuscript that has been accepted for publication. is providing this early version of the manuscript as a service to their readers.) Open Access:
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Vinay Prasad 3. velj
I enjoyed reading this article about companies that are moving into the space of A blood test to screen for cancer They have an uphill battle that I fear they do not yet fully recognize [Thread]
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\mathfrak{Michael "El Muy Muy" Betancourt} 2. velj
Intro physics experiments are more complicated than expected but that's what makes them perfect for demonstrating the utility of Bayesian modeling. In my most recent case study I try to infer gravity from falling ball data and find a few surprises: .
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Sam Finlayson 4. velj
Odgovor korisniku/ci @venkmurthy @drkevinknopf i 2 ostali
Great point. Whole body CT is definitely a better analogy than 23andMe, in my opinion. I wonder if whole body CT was also held back because the potential harms from radiation was probably more obvious in a big noisy scanner than are the more epidemiological harms.
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Sam Finlayson 4. velj
Odgovor korisniku/ci @drkevinknopf @venkmurthy i 2 ostali
To be clear, I was commenting on the market, not the actual health value to that market!
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Sam Finlayson 4. velj
Odgovor korisniku/ci @venkmurthy @VPrasadMDMPH @23andMe
These *feel* like different markets to me--or at least a very different pitch. ctDNA would be serially ordered and (be sold as) immediately actionable health information/alt to colonoscopy, etc. 23andMe is 1 time, and even then for most users buy it either for geneology or fun.
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