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Erika Doxtader 8 Nov 18
Decoy cell (polyomavirus cytopathic effect) in urine cytology. Nuclear chromatin homogenization is typical. The nucleus is big but the nuclear membrane is smooth, not irregular. Don’t call this high grade urothelial carcinoma!
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Michael P. Lee MD 6 Sep 18
Perhaps the most gorgeous case I have seen of extra-mammary Paget's disease. This case doesn't show the typical pattern where tumor cells compress (flatten) the underlying keratinocytes. Bonus questions: What panel of stains would you get and why?
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Abubaker Elshaikh 26 Jan 18
Mycobacterium Avium Complex (MAC) infection: Blunted or normal villi distended by diffuse histiocytic infiltrate. AFB and PAS show abundant acidfast bacilli within histiocytes.
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Erika Doxtader 27 Jul 18
Cellular changes consistent with Herpes Simplex Virus. Pap test. 3Ms: 🔆 Multinucleation 🔆 Molding 🔆 Margination of chromatin
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Frank Ingram, MD Oct 22
BIRADS 4 lesion. Boards question...what bug is associated with this histologic finding?
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Christina Arnold, MD Sep 18
Replying to @CArnold_GI
7/ -Our clinicians order mass spec analysis on every amyloid case (thank you Mayo Clinic Rochester!) bc it guides their management. -AL type: Most common, will trigger a lymphoma workup (imaging to look for big LN/spleen/masses, SPEP/UPEP, bm bx
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Abubaker Elshaikh 7 Feb 18
Medullary thyroid carcinoma: Solid sheets and nests, separated by fibrovascular stroma. Cells has a salt and pepper nuclear chromatin. Strong inherited association with MEN2A and 2B.
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Pallavi A. Patil, MD 7 Oct 18
Lactose fermentation on McConkey agar causes pink color development that also forms halos around colonies. Compare this lactose fermenting E. Coli with pigment producing Serratia that is pink without halos on McConkey, producing pigment even on blood agar
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Aaron D. Shmookler 9 Oct 18
The Tech Manual has a great chapter on DAT. Nice summary table distinguishing Warm, Cold, PCH, and Mixed. Don’t forget drug and infections etiologies (plenty of high yield rat-facts here )
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Aaron D. Shmookler 30 Oct 18
Replying to @HermelinDaniela
A3 subgroup classically has mf (). Using a variety of biochemical techniques including NMR, Mass Spec, and TLC Svensson et al. suggest it may be due to weak A antigen expression and lack of glycoprotein branching.
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Frank Ingram, MD 22 Feb 18
Hello, Twitterpath friends. Check out this funny-looking uterine fibroid. Is there any other testing you would recommend for this patient?
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John Sherbeck MD 13 Aug 18
PJP (aka PCP) infection on BAL. Frothy debris filled with “crushed 🏓 balls” on GMS.
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manuel lora gonzalez 19 Jan 18
I am going to be so disappointed if this IHC comes back negative.
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shelley Oct 15
Replying to @feldstej
Loving the hashtag....
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Eman Aljufairi, MD 15 Jan 18
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Olca Basturk Nov 26
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Paul M. Gibbs 27 Nov 17
Pelvic mass, male, mid-20s. What is the characteristic translocation? Classic .
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Eman Aljufairi, MD 14 Nov 17
This made my day 🙃Granular cell tumor usu benign but can be worrisome on radiology bcs infiltrative. Rx is excision. DDx: granular leiomyoma
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Christina Arnold, MD 1 Oct 18
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manuel lora gonzalez May 22
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