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Aurelia Bioscience Jul 18
See what’s up in our lab this week! Here’s some data from 's Target Engagement Intercellular Kinase Assay. It shows active compounds binding to our target . Find out more about our expertise here:
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Cisbio Jul 18
No idea of the best tracer to use for your binding assays 🤔? Download the 3 application notes to find out.
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Emma Pettengale 🧬🦠🔬 Jul 18
A great talk showing a novel mode of regulation of the PI3K regulatory subunits underpins the proliferative potential of the Cdc42 activated tyrosine kinase from Millie Fox
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Emma Pettengale 🧬🦠🔬 Jul 18
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IUBMB Jul 19
Submit an abstract for the IUBMB Focussed Meeting on Protein Kinases IPK2019 - August 15 deadline - best poster award and great science in beautiful Warsaw. Register:
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Reaction Biology Jul 17
inhibitors that are clinically used to treat cancer increased the likelihood of CXCR4 activation of Akt and/or ERK, suggesting that such drugs may inadvertently promote pro-metastatic CXCR4 signaling
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Molecular Metabolism 24 Nov 17
Absence of the mimics the effect of chronic endurance on tolerance and For the article: For all 60 Second Metabolist videos:
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Nature Cell Biology Sep 24
Jin Zhang and colleagues create single-fluorophore sensors for PKA, PKC and ERK in different colours, and demonstrate that they enable multiplex imaging of a combination of signalling activities in cell lines and primary rat neurons
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UTSW Radiation Oncology Jun 18
Meet Ken Westover, M.D., Ph.D., Associate Professor. He is a practicing thoracic radiation oncologist, biochemist, and structural biologist focused on improving cancer outcomes through innovation in radiation therapy and drug discovery.
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enzymlogic 28 Jan 18
Selective inhibition of NF-κB inducing in vivo leads to inhibition of multiple pathways involved in systemic lupus erythematosus.
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Prita Riana Asih May 15
Dr Arne Ittner gave an excellent talk on protein kinases, tau, and Alzheimer's disease at Dementia Research Centre Scientific Meeting at Macquarie University
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Newton Lab Feb 20
Catching a beautiful San Diego sunset with BMS faculty Natalia Jura, after her eloquent and beautifully-illustrated seminar in Pharmacology Seminar class.
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Matthias Mann Lab Mar 14
Take a look at our exciting paper in metabolism showing changes in pancreatic islets. We discovered that GSK3 plays a central role in the development of type 2 diabetes. Targeting GSK3 restores secretion of diabetic islets.
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JCellBiol Jul 19
Tripathi et al show that phosphorylation by SRC & ERK mitigates DLC1’s tumor suppressor activities but these can be reactivated by inhibition as a potential treatment
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Onisha Patel May 26
A fold evolved to do other things like polyglutamylation using ATP but using another ATP binding site distinct to the conventional site. Mechanism to give advantage for bacteria to survive in the host. We think we know enough about kinase fold but actually we don’t!
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Bayliss Lab 15 Mar 18
How Aurora-A recognises its substrate TACC3, how phosphorylation orders TACC3 and how this is recognised by clathrin - there's something for everyone* in our latest publication!
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Newton Lab Apr 18
PKC autoprotecting its phosphate from the sniffing phosphatase PHLPP, to ensure its stability. Thanks O’Reilly Science Art for capturing the essence of our work 🐶 🎾
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Onisha Patel 31 Jan 18
Please help RT. If is your thing then apply with Isabelle Lucet & myself . We support diversity, , creativity, .
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Javin Oza Aug 16
Our first successful higher throughput assay that's going to allow us to pursue detailed human enzymology. All because of 's focused efforts.
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Goodwin Laboratory Aug 2
Manzamines from Indo-Pacific sponges inhibit Mycobacterium shikimate . The latest from our collaboration with the Calderón and Hamann Labs
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