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Cancer Dependency Map Sanger Jul 24
New data available on the Project Score CRISPR database. We have processed the Broad Institute 19Q2 dataset (492 cell lines) through our analysis pipeline and it is now available as a downloadable file here ().
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DepMap Aug 9
REPURPOSING HUB DATA AND PREPRINT NOW OUT!! See how >4500 existing compounds performed when used across >550 cancer cell lines 💊 , data can be found on the portal:
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Garnett Lab Dec 18
Looking to do exciting new science and progress to the next step in your career? We have a Senior Staff Scientist position available in functional genomics to help lead a team building genetic interaction maps. (). Part of . Please RT
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Tirosh Lab Jul 25
A nice read on aka Mapping weak spots in cancer
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Garnett Lab Nov 4
It was an honour today to receive the NCRI Innovation award at for our work on tumour organoids. Thank you to the team and our collaborators in the UK and abroad, and the patients who contribute tissue. These models are part of .
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Cancer Dependency Map Sanger Mar 3
New data release from GDSC project includes 60,434 new IC50 values from 70 additional compounds. The total dataset now includes 446,000 dose response curves for 565 drugs. All available through the GDSC data portal: @https://www.cancerrxgene.org/
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Kenichi Shimada Dec 19
Here's the link to the tool, shinyDepMap:
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Rachel Apr 10
a new approach to finding cancer drug targets
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Emanuel Gonçalves Jan 15
Our latest is up on “Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens”. Great collaboration between and
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Emanuel Gonçalves Nov 21
Our most recent work is now up on describing a ‘Minimal Genome-wide Human CRISPR-Cas9 Library’
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Garnett Lab Oct 29
Come join us and work on this exciting project at the interface of immunoncology and functional genomics. Translational science to try and help patients.
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Saez-Rodriguez Group Apr 11
Behan, Iorio, Picco et al. Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens - led by & Yusa labs, genome-wide CRISPR screens in 324 cell lines w analyses from our former
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Fiona Apr 10
1 in 2 of us will get a cancer diagnosis in our lifetime but initiatives like between and fill me with hope that the beat treatments will be available.
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Kenichi Shimada Dec 19
Our paper introducing a web-tool to explore the DepMap is now on biorxiv!
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Sanger Institute Oct 8
Congratulations to Mathew Garnett, who has won the Innovation Award for his work with in producing cultures to accelerate cancer research 🧫🔬
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Garnett Lab Oct 28
Mathew will be presenting a poster today at on the Cell Model Passports - a hub for cell model clinical, genetic and functional datasets. Come and learn more or give us suggestions on how to improve the site. Poster B-69.
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DepMap Feb 7
New 20Q1 now available! Data for 44 new cell lines, plus newly integrated proteomics data from +
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Garnett Lab Jan 8
A reminder that we have an opening for a Senior Staff Scientist to help lead a team building genetic interaction maps. Closing Jan 18th. This is a great opportunity to do cutting-edge collaborative science. Don't miss out!
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DepMap Sep 23
Wonderful to have the Cancer highlighted in a talk last week! Honored to be part of the efforts to enable scientists around the world to push the boundaries of cancer research. 🙌
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Cancer Dependency Map Sanger Dec 20
This study is a great example of how early data sharing and collaboration can produce useful tools and insights for the community. Congratulations to everyone involved!
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