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Eric Topol Jun 11
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Josiah Zayner Jun 13
The thing that alot of people forget about is that it just cuts DNA. In practice, it is no different than Zinc-Finger-Nucleases or TALENs. All cause double strand breaks, all have off-target effects. All of this stuff has been studied before, all will be studied again.
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Gaetan Burgio Jun 14
This is a great one on the generation of point mutants in mouse using base editor -> Efficiency is really high ~ up to 100% point mutants & highly specific (aka no Off target effect) -> amazing results
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Thorsten Bausch Jun 14
The weirdest declaration I ever saw on the EPO register. Submitted in EP2771468 . Is this a hoax?
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Gaetan Burgio Jun 11
1) Beware exaggeration and overstated headlines. The papers say after Cas9 DSB P53 signaling is activated. They don't say could cause 2) One of the paper was posted a year ago on BioRxiv server -> not a new finding
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Stuart Smyth Jun 15
It's great to see the supporting technologies based on rather than categorically rejecting it like & . supports child stunting & food insecurity by rejecting . , why do you do this?
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Louise O. Fresco Jun 15
On behalf of the entire community I congratulate Prof. John van der Oost with the National Spinoza Prize! He & his super team will invest €2.5 million to fund new research on immune systems: to improve resilience in crops & to tackle hereditary diseases in animals
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sharon begley Jun 9
1st use of in : sci's KO myostatin gene to create red sea bream ( delicacy) w/16% more skeletal muscle, the stuff you eat. Fastest fish breeding (2 yrs) ever:
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Adrian Percy Jun 8
The possibility of rice plants producing even more grains may not be far off thanks to technology. One major barrier? Consumer acceptance. Once that’s tackled, the impact could be huge.
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Petra Jorasch Jun 14
I had the privilege to taste cabbage last year in Sweden. Great experience 😊
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Nature Medicine Jun 14
–Cas9-induced DNA damage triggers p53 to limit the efficiency of in human pluripotent cells:
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Varro Analytics Jun 11
Jan 2018: stocks decline on commensal bacteria preprint. The data had been shared at conference 15 months prior. June 2018: stocks decline on P53 Nature paper. A preprint was published 11 months prior. And they say the market is efficient...
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Allen Institute Jun 11
Using gene-editing technology, our Institute for Cell Science researchers illuminate key structures in healthy human cells. Over 20 fluorescently tagged hiPSC lines are available via to support research worldwide.
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DAVIDSON_LAB Jun 14
A nice feature in Nature about our work!
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GMWatch Jun 11
Swiss Federal Ethics Committee Defends Precautionary Principle in Regulating New Biotechnologies
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Biomedical Journal Jun 7
Francisco Mojica to share CRISPR story in Sydney next week. discovered the repeats in 1992. The repeats, which turned out to be a microbial immune system to ward off invading viruses, opened the door to the world of genetic engineering.
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Premas Life Sciences Jun 13
"Using genome-wide and high-density CRISPR-Cas9 “tag-mutate-enrich” mutagenesis screens, we identify close to full-length mutant forms of PARP1 that cause in vitro and in vivo PARPi resistance"
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April Pawluk Jun 16
Can’t wait to catch up with everyone and hear about cool new science stories this week at ! Especially excited for the panel & for the chance to represent at one of my favourite meetings!
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Ritsuya Niwayama 2h
A wonderful job on transgenesis. injection to 2-cell embryo will need nice training, and the usability will depend on the stability of microinjection systems of individual labs.
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GEN Jun 10
Supplement: -- Moving Gene Editing from Basic Research to the Clinic:
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