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Robert W. Yeh MD MBA 23 Sep 18
First thoughts on - a blow out. MitraClip won across the board. It wasn’t close - very meticulously conducted, including very carefully selected population - effectiveness in real world will hinge on how closely docs can replicate enrolled pt group
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John Mandrola, MD 23 Sep 18
MitraClip for secondary MR — The Redux My thoughts on the astonishing trial on
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Said Alsidawi 23 Sep 18
The number of MitraClips is about to spike. This is a good thing as an interventional echocardiographer. However, please don't refer a patient while still on 2.5 mg of lisinopril and 3.125 mg of coreg. This is still inappropriate.
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Rohan Khera 23 Sep 18
Dear interventional cardiology fellow friends. Maybe just go ahead and do that 2nd structural year you have been debating about.
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John Mandrola, MD 23 Sep 18
Here’s another # matter that warrants discussion h/t Stay tuned.
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Dr Andrew D. Choi 23 Sep 18
There’s a crucial role to refine current curriculum & training pathways in structural imaging. We hope to spark approaches that incorporate both CCTA & echo. This is a complex issue in the care of complicated patients seeking a collaborative solution!
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Ahmad Masri 24 Sep 18
And so too true to believe? At least during the first year, it was a better conducted trial as compared to Mitra-FR. Comparison here and a quick meta-analysis at 1 year -- but HF numbers taken from KM curves, not accurate enough. Mortality reported.
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eric horlick 23 Sep 18
Coapt is positive! Decreased hospitalization and all cause mortality in patients with secondary mr maximally treated for heart failure with mitraclip Vs medical rx alone . NNT = 6 to save a life. Outstanding news for our patients!
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James D Thomas, MD 23 Sep 18
Dramatically positive results from the trial. Number needed to treat to save a life at 2 years: 5.9! Great collaboration of echo, heart failure, intervention and surgery giving more options for our patients.
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Muthu Vaduganathan 23 Sep 18
Wow, congratulations to the investigators & leadership - a new era in interventional HF management. Transcatheter Mitral-Valve Repair in Patients with Heart Failure | NEJM
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Juan F. Granada 23 Sep 18
Another lesson learned; never underestimate the power of well performed clinical trials; few trials deliver conclusive evidence of a solid biological effect...
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Ajay Kirtane MD SM 23 Sep 18
Important lesson from vs. MITRA-FR: need to revisit what simpler "pragmatic" trials actually tell us. Ultimately no substitute for carefully conducted study. Yes pts were carefully selected after GDMT, but that is how we should practice & where device has role
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Ethan Korngold, MD 23 Sep 18
Spotted: earrings. For real.
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Ethan Korngold, MD 23 Sep 18
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Atrium Health 16 Mar 19
For more than a decade, Sanger has brought minimally invasive heart valve treatments to patients. At the Scientific Session, researchers will share how some of these treatments influence quality of life. Dr. Michael Rinaldi, a co-author of , shares more.
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Nir Uriel, MD MSc 23 Sep 18
Live from Congrats to trial investigators on this potentially practice changing result, how do you reconcile these results with recent Mitral FR trial? Patient selection/operator dependent?
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RTHahnMD 23 Sep 18
COAPT IS A WIN for patients with heart failure and significant MR! Bravo to all participating in this landmark trial!!
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Pradeep Natarajan 23 Sep 18
Evolution of Mitraclip studies reflects improvement on proceduralists' proficiency & focusing on more severe but not too severe MR - NNT 3 for CHF hospitalizations and 6 for death at 2y 👏
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Nadeen N. Faza, M.D. 14 Mar 19
💥 BREAKING NEWS 💥- FDA approves for functional MR. Great news for many patients with debilitating symptoms!
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C. Michael Gibson MD 24 Sep 18
We found Dr. David Cohen () sneaking a Big Shoutout to Mom from so we invited him in for a chat! Watch my interview with Dr. Cohen, co-author of the trial, on adding life to people's years and not just years to people's lives:
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