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Greg Jefferis
@
gsxej
Cambridge, UK
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Neural Circuits and Behaviour in Drosophila @MRC_LMB. PI @flyconnectome @CamZoology and @virtualflybrain. Tweets my own.
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Pratim
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1.673
Osobe koje vas prate
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Greg Jefferis
@gsxej
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1. velj |
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If we knew what the cell types were in really big datasets with fine scale typing based on other information, then maybe we could define better predictive models to apply to raw gene expression data.
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Greg Jefferis
@gsxej
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1. velj |
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I’m sure connectivity is more defining, but I’d actually be surprised if there isn’t also a reliable transcriptional signature. Since very little rnaseq data comes with connectivity/morphology, analysis is mostly unsupervised cell type discovery.
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Dr Naomi Moris
@nmoris
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30. sij |
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For any female postdocs or graduates at @Cambridge_Uni , who want to conduct research or fieldwork abroad - apply to be a Gibbs Travelling Fellow at @Newnham_College now! Happy to answer any Qs about the role if I can #WomenInScience twitter.com/Newnham_Colleg…
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MBA (Marine Biology)
@thembauk
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30. sij |
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We are delighted to announce that the prestigious, two-week 37th Microelectrode, Patch Clamp and Optical Techniques for Cell Physiology Workshop, hosted by the MBA (Plymouth, UK) is now open for applications! ow.ly/27mj50y8SwK pic.twitter.com/1WAsNA0z9H
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Greg Jefferis
@gsxej
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31. sij |
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Last sentence of the abstract reminds me of @neuroluci @bentonlab “We propose an enhanced evolutionary capacitance of olfactory sensory neurons that enable the functional expression of odorant receptors with cryptic mutations.”
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Dagmar Kainmueller
@kainmuellerd
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30. sij |
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We’re looking for a PhD student to work on Deep Learning from Sparse Annotations for Cell Segmentation in the HEIBRiDS grad school in Berlin (application deadline Feb 7): heibrids.berlin/admission/
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Isacoff Lab
@IsacoffLab
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29. sij |
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Catherine Perrodin
@c_perrodin
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30. sij |
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biorxiv.org/content/10.110…, a thread (featuring mice, songs and love):
Did you know that male mice sing elaborated, ultrasonic “love” songs to attract females? All this at frequencies so high-pitched that they are inaudible to humans? (1/6) pic.twitter.com/JOzgskCrWf
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Stephen Plaza
@stephenplaza
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29. sij |
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We are maintaining a list of known #hemibrain issues that are mostly straightforward to address: docs.google.com/document/d/1va…
A couple technical details in the following thread...
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Simon Bullock
@SimonBullock11
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29. sij |
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Does anyone know of someone in the UK culturing #tardigrades? Am looking from new live subjects for our schools microscopy project (www2.mrc-lmb.cam.ac.uk/microscopes4sc…). Currently use Daphnia, Volvox, Tetrahymena, Paramecium. Other suggestions welcome.
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Greg Jefferis
@gsxej
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29. sij |
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Thanks a lot for the highlight, Kevin! Thread with further details here twitter.com/gsxej/status/1…
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Greg Jefferis
@gsxej
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29. sij |
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Thanks, Simon! Please see thread for more details twitter.com/gsxej/status/1…
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Greg Jefferis
@gsxej
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29. sij |
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Thanks! See thread twitter.com/gsxej/status/1… for more details.
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Greg Jefferis
@gsxej
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29. sij |
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We are grateful to long-term support from @royalsociety (to @SebaCachero) @MRC_LMB and @ERC_Research. We will continue to refine the system in flies and we believe that #BAcTrace has promise in other organisms including fish and mice. 10/11
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Greg Jefferis
@gsxej
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29. sij |
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Flies will be deposited @flystocks when the manuscript is accepted. Please contact us if you are interested in obtaining stocks ahead of time. We will ask that you send us feedback on how #BAcTrace works for you! 9/11
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Greg Jefferis
@gsxej
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29. sij |
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Rabies has been engineered to act as a retrograde tracer, revealing all the inputs to a neuron. However limitations include toxicity and uncertainty about which synapses it crosses. Furthermore, these viruses are not applicable to all species. 2/11
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Greg Jefferis
@gsxej
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29. sij |
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#BAcTrace, a #tweeprint: At least since Francis Crick’s famous review of 1979, neuroscientists have dreamed of ways to identify all the neurons connected to a cell of interest. In the last decade this has become a reality through the widespread use of rabies virus tracers. 1/11 twitter.com/biorxivpreprin… pic.twitter.com/nVGKPvCexH
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Greg Jefferis
@gsxej
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28. sij |
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Just to be clear that the majority of cells in eg Drosophila brain are not *identified neurons* in the sense of just one cell per hemisphere. Instead, they are members of an identified cell type occurring in 2,3,5 or sometimes even several hundred copies per hemisphere.
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Greg Jefferis
@gsxej
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28. sij |
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Sorry, we spotted soonish that you weren’t @dddavi but unfortunately it was already too late!
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Bill Hansson
@billhansson
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27. sij |
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Today the Grand Opening of nGICE took place at SLU, Alnarp. Starting up around 15 PhD students and postdocs to unravel the effects of climate change on insect chemical communication. pic.twitter.com/0NH8wFSWFa
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