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Ryan Radecki
Emergency Medicine & Clinical Informatics. NW Permanente, University of Texas Medical School at Houston & Annals of EM. &
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Ryan Radecki retweeted
Sarah Andersen 10h
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Ryan Radecki 7h
Replying to @biomerieuxcmo
I'll give you credit for that one, but when my feed looks like ....
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Ryan Radecki 9h
The insightful input of the PCT assay sponsor robot, issuing the same reply to everyone who comments ....
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Ryan Radecki 10h
I think it's more likely the tightly controlled trials conducted by the sponsor do not reflect practice. In "real world", PCT grossly over-ordered, as well. But, yes – this is not an inpatient stewardship trial, it's primarily an outpatient LRTI trial. Different domain.
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Ryan Radecki retweeted
George Alba, MD May 20
this just in from ~ trial of VV-ECMO for severe ARDS stopped for futility: no significant difference in mortality at 60 days compared to conventional MV but reduced 2ndary endpoints and 28% cross-over to rescue ECMO with improved survival.
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Ryan Radecki retweeted
jeremy faust May 22
In a related story, Boehringer Ingelheim makes Praxbind™️!
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Ryan Radecki May 22
Underpowered to show differences in subgroups; should be considered exploratory, but Bayesian considerations consistent with other literature. Adherence was big problem – but reflects pragmatic and real-world inappropriate use of PCT. Lots of issues at play here.
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Ryan Radecki May 21
A definitive takeaway from this large procalcitonin trial is unfortunately crippled by poor protocol adherence.
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Ryan Radecki retweeted
Seth Trueger May 21
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Ryan Radecki May 18
Replying to @EMNerd_
A less-experienced operator was relieved of the tools with which he was most comfortable in cases where some difficulty was expected.
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Ryan Radecki May 18
ICYMI: Beware the coming impetus for empiric tPA in "wake up stroke", despite the imaging criteria necessary in this trial:
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Ryan Radecki May 18
Replying to @EMNerd_
... but if you have training programs where they routinely use the bougie and VL for airways of moderate difficulty, taking the bougie away from them will bias the results away from the null.
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Ryan Radecki May 18
- When you’re a PGY-3 resident. - When you’re trained to use the bougie routinely. - When you do all your intubations via C-MAC video laryngoscopy.
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Ryan Radecki retweeted
Skeptical Scalpel May 18
Locking pliers are not commonly used in brain or Jello surgery.
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Ryan Radecki retweeted
Jay Khadpe May 17
Replying to @emlitofnote @JWatch
Also would disagree with the strength of the reviewers conclusion in the comment box. Limited benefit with increase in emesis and no mention of increase in cost/resource utilization. Would like to see more appropriate primary outcomes measured.
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Ryan Radecki May 17
"This study was funded by the Multiparty Group for Advice on Science (MUGAS) Foundation through an unrestricted grant from Roche Pharmaceuticals." "A. S. M. reports receipt of consulting fees from Roche related to the submitted work"
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Ryan Radecki May 17
Replying to @BrooksWalsh
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Ryan Radecki May 17
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Ryan Radecki May 17
A narrow application of MRI to determine tissue viability in acute stroke seems likely to fuel calls for expanded (irresponsible) use of tPA.
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Ryan Radecki retweeted
Brian Doyle May 15
Replying to @emlitofnote
What about harms of fasting? Prolonged ED stay, greater use of resources etc. Not to mention death by fasting! (root cause of tragic incident below)
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