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Daniël P Melters
How did holocentric chromosomes evolve? And what can it tell us about the evolution and adaptation of chromatin domains?
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Daniël P Melters Jul 11
Our updated manuscript is online: Intrinsic elasticity of nucleosomes is encoded by histone variants and calibrated by their binding partners
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Daniël P Melters Jul 10
Replying to @Duke_of_neural
Relative of the shipworm eat rock to produce sand:
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Joanne Emerson Jul 9
Our group at UC Davis is looking for a soil viral ecology/bioinformatics postdoc! Omics experience very helpful, virus background not required. Apply by Aug. 9 for full consideration.
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Daniël P Melters Jul 8
It was wet this morning.
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Daniël P Melters Jul 7
Replying to @mimperia @DaveJWWynne
What I was told is that freezer companies back in the day used their lowest temp as a marketing tool under the assumption that colder is better. Not so much evidence based. What I got is: increase temp to guarantee safe storage of your samples while using much less energy.
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Daniël P Melters Jul 7
Replying to @PracheeAC
First MS/PhD in my family. Lost my sister while studying for my qualifying exam. Lost my last grandparent. Lost one of my PIs during my last year in grad school (=5 yrs). Made possible by: 2 smart and strong daughters by age 33. And of course a massively supportive better half!
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Dr Janine Krippner Jul 3
Our records show a near-continuous eruption at Stromboli since 1934. You can learn more here:
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sue biggins Jun 28
Faculty position for a structural biologist utilizing cryoEM...come join us. Please RT!
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Seth Donoughe Jun 27
Did you know that insects have evolved flight feathers? And it’s happened at least THREE separate times? This is a brief thread describing recent work on the structure and scaling of insect feathers, such as this one from the beetle family Ptiliidae:
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Anders Sejr Hansen Jun 26
C Haering & et al. have done it again. Loop extrusion by SMC complexes is more complicated than we thought. Pairs of condensins can come together to form Z-loops and achieve bi-directional extrusion. Lots to digest. Please tweet some movies :)
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cees dekker Jun 26
Preprint of our &HaeringLab on DNA loop extrusion by SMCs Many surprises here: - Loops can mutually exchange size - Condensins can pass one another! - to form totally new type of ‘Z’ loops - that may fill DNA gaps
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Daniël P Melters Jun 25
Replying to @TeamCentromere @NIGMS
Congratulations!!
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Job Dekker Jun 21
Our latest preprint is out: how cells convert the mitotic chromosome folding state into the interphase state. Great work by Kristin Abramo, Anne-Laure Valton, Sergey Venev, Hakan Ozadam and Nicki Fox.
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Daniël P Melters Jun 21
Curaçao 🇨🇼!!!!
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Daniël P Melters Jun 21
There is no histone without its variants —> Novel histone H4 variant H4G regulates rDNA transcription in breast cancer
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Daniël P Melters Jun 20
That was a mighty performance by in the against the local giant . They were a joy to watch and deserved a draw which was so close by. Keep shining!
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Lou Charkoudian Jun 20
breakfast conversation houseguest: I try to eat food without chemicals 6y/o: all food has chemicals 3y/o: we are all made of chemicals 6y/o: and bacteria... which I guess are also made of chemicals. houseguest: husband (raises eyebrows at me): nice work, lou me: 🥰🥰🥰
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Ed Yong Jun 20
In the late 80s, an Inuit hunter killed a strange whale and kept its skull on his roof for years. A new study finally confirms that the animal was a narluga--a hybrid whale born to a beluga father and a narwhal mother.
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Carl Zimmer Jun 18
Your arm and an octopus arm are built by the same genes. For my column this week, I look at a striking new case of “deep homology.”
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Denis Titov Jun 18
We're looking for an ambitious postdoc to lead our New Innovator Award project studying metabolism and aging in C. elegans using novel approaches and tools. Details: Please RT!
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