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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš…
1) why you can't class humans into two categories by genitals. Some science.
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
2) a glance between a newborn's legs is a pretty good indicator of their sex. However, it isn't a foolproof method, and here, in simplified terms, is why.
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
3) you all know the egg and sperm sitch. A sperm gets into the egg and that good old magic happens that results in a future taxpaying voter. The deal is you get half the dna of your egg and half from the sperm. Switcharoo presto, and you got a new sequence of DNA. Noice.
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
4) a chromosome is a packet of DNA, and when it comes to sex, you probably where taught that the X and Y chromosome is how we get boys and girls. An X meets an X, you get a pink crib, an X meets a Y and you get a blue one. Right?
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
5) the sperm either has an x X or a Y. So daddy picks the sex. (Someone tell Henry VIII) But the problem is that is where our education usually stops.
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
6) let's go a bit deeper so you are a bit wiser. The important part of the Y gene which makes it chocked full of manly goodness is called the SRY region. Infact it appears to be the only important part in deciding sex. It's basically the order form for a boy. Nothing more.
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
7) the rest of your DNA contains information to make both a boy you and a girl you. By default, the boy stuff is basically switched off. Like dip switches on a computer.
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
8) if you have the SRY region, that kicks off a chain reaction the *usually* results in cheaper haircuts and better wages... aka, manhood. But not always.
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
9) the important thing to understand is the chain reaction. I need to set some ground work first. Ovaries and testes both form from the undifferentiated gonad. No SRY? Ovaries. SRY? Usually testes. Let's say the tested form as usual, they will start making androgens.
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
10) androgens are hormones such as testosterone and dihydrotestosterone (which makes you bald btw). The growing fetus emits two baths of androgens during two stages of its development. So what does it do?
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
11) well, here's the thing. As I said, your dnd has both sets of instructions- male and female. Our cells actually don't give a crap which set they use, they just go with the one they have activated. How is that DNA activated? By hormones. Specifically here, androgens.
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
13) cells have androgen receptors on the surface. Androgens snap to that shit like a key to a lock. Once that happens the receptor enters the nucleus of the cell and does a sort of tumbler thingy to your DNA, turning some bits on and some off.
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
14) the cell then does it's thing, eventually dividing and the process continues... bind, activate/deactivate DNA... do whatever the cell does and divide...etc etc. So you start developing sex characteristics based on whatever hormones you have AT THAT MOMENT
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
15) so this is where genitals form. Yay. Very handy. Genitals all start as a bunch of ducts that slowly develop or self destruct depending on what hormones are around. Are you starting to see what I mean?
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
16) The Mullerian duct, for example, grows up to be the upper third of the vagina, womb and fallopian tubes. If the hormone AMH is around, it withers away. (Women who make AMH are missing their wombs.)
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
17) the clitoris and the penis develop from the same tissue. Take a good look at a clitoris and you will see it is very similar to a teeny penis head. If you get those androgen baths, the clitoris develops into a penis... sometimes big, sometimes very little... and here...
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
18) comes challenge number one... how big does a clitoris need to be to be classed as a penis? Hmm? Okay lets aim down a bit. The labia and the scrotum also start as the same tissue. The labia fold over and fuse, forming the sack... that's why scrotums have that little seam
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
19) the ovaries stay still or, if if androgens are about, begin being tugged down into the scrotum. Slam dunk. Nothing but net. Except... you know sometime the labia don't entirely fuse. You get something that kinda sorta is a vulva... but kinda sorta not...
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
20) challenge two: is it a vulva or an open scrotum? Who gets to decide? And why? If you want to know where the wee hole can end up in all this, google hypospadias.
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Delaney KingπŸ”±βš€βšβš‚βšƒβš„βš… Oct 21
Replying to @delaneykingrox
21) see, all the way along this chain reaction, from egg meeting sperm, to cell division, to gonad formation to hormone reception that chain reaction can vary. Throw in cell mutation and chemical interference and wow, do you have a lot of variation.
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