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Dr. David Ludwig
Physician, Nutrition Researcher, and Public Health Advocate. #1 NY Times bestselling author of ALWAYS HUNGRY? and cookbook ALWAYS DELICIOUS
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Dr. David Ludwig 6h
Replying to @whsource @erik_arnesen
PS, not arguing that GL explained the whole effect in the ultra-processed food study, just part. The difference in energy density probably played the major role over 1 to 2 weeks.
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Dr. David Ludwig 7h
Replying to @whsource @erik_arnesen
Here's the other panel from that figure, looking at diet effect among high insulin secretors (half the cohort). About 10 lb persisting at 18 months.
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Dr. David Ludwig 7h
Replying to @leoniee54
Food industry is not going away, nor is food processing, so we need to know how to guide them correctly. Consider apple juice versus olive oil. Both are single nutrient plant extracts: sugar versus oil. But one is associated with obesity and diabetes, the other is protective.
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Dr. David Ludwig 14h
Try the Abstract: "Limiting consumption of ultra-processed foods may be an effective strategy for obesity prevention and treatment."
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Dr. David Ludwig Jun 23
Replying to @FiberCarb @tednaiman
Herein lies the (rather subtle) distinction between: low carb HIGH PROTEIN, moderately high fat VERSUS very low carb, mod protein, VERY HIGH FAT.
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Dr. David Ludwig Jun 23
Replying to @janvyjidak @tednaiman
Substitute, not add, and include protein. Instead of a whole bagel and fat free cream cheese, have a half a bagel, real cream cheese and smoked salmon.
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Dr. David Ludwig Jun 23
Replying to @tednaiman
How about simplifying? If glycemic load stays low, then the “avoid carbs + fat” becomes moot.
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Dr. David Ludwig Jun 23
Support, yes. But we need prospective studies looking at time course for confirmation. The key would be that high insulin secretion precedes insulin resistance (or is relatively greater early). There is clear evidence of this in animal models.
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Dr. David Ludwig Jun 22
We've discussed the problems of these very short studies, when it comes to fat adaptation. Need randomized studies of at least a month to make meaningful conclusions about low carb diets.
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Dr. David Ludwig Jun 21
Looks like they didn’t get past the third day. (Probably lacked adequate salt, etc). They claim a keto diet can’t be sustainable. Of course we know that’s wrong, from millions who’ve followed it (and Native Americans who ate pemmican as sole ration for extended periods).
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Dr. David Ludwig Jun 21
Replying to @cadiulus @stanhywet
You clean up (from those muddy jogs) nicely!
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Dr. David Ludwig retweeted
HarvardPublicHealth Jun 21
The U.S. military is considering putting its elite Navy SEALS on the high fat, ultra-low-carbohydrate ketogenic diet. spoke with about the science behind keto.
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Dr. David Ludwig Jun 19
Weight Stigma is Not New. “Obesity is a disorder which, like venereal disease, is blamed on the patient.” 👉EB Astwood, 1962, as quoted by George Bray during his brilliant awards lecture at Am Soc Nutr”
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Dr. David Ludwig Jun 17
Ted, didn’t recognize you with a shirt 😂
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Dr. David Ludwig Jun 17
Replying to @BrianQuiz
Reducing consumption of processed (high glycemic load) carbohydrates lowers insulin secretion immediately. There is some evidence that, over time, insulin producing cells calm down, and secrete less insulin in response to carbohydrate, as in this study:
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Dr. David Ludwig Jun 17
Remarkable study indeed! 👉 Evidence that high insulin secretion precedes insulin resistance 👉 AND evidence that high insulin secretion may drive weight gain. Of course, women typically gain weight (excluding fetus and placenta) faster in pregnancy than at any other time of life
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Dr. David Ludwig Jun 17
Diabetes in pregnancy threatens mother & child. How should we treat it? 👉Dietary guidelines were developed with "low rigor, lack of multidisciplinary stakeholder involvement, low applicability, and inadequate editorial independence." 👉Need to do better
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Dr. David Ludwig Jun 14
Replying to @MaraMather
Yes, well funded for a diet study. 👉Still a tiny fraction of the cost of a major drug study (eg, for just one diet-related condition, like high blood pressure or high cholesterol)
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Dr. David Ludwig Jun 14
On intermittent fasting, ketogenic diets, and drugs like metformin: 👉"if found to be safe and effective in clinical trials, interventions targeting glucose metabolism could act as low-cost combinatorial adjuvants for cancer patients." 👉Research needed
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Dr. David Ludwig Jun 11
A riveting read, from Harvard Med’s previous Dean. Full text freely available.
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