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Adam Marblestone
Technologist, Scientist
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Nature Biotechnology 3. velj
A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy
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Sarah Constantin 30. sij
You know how hypothalamic function declines with age? This paper seems to isolate an essential mechanism for that, and shows that it can be reversed. (In mice, of course.)
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hardmaru 30. sij
Another reason to write blog posts
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Celine Halioua 29. sij
This is important bc one of the biggest arguments pharma makes against price control of new medicines by US Govt and quicker generic medicines access is that the cost to develop the new drug would be larger than the predicted ROI of the drug
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Adam Marblestone 29. sij
Odgovor korisniku/ci @AdamMarblestone
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Adam Marblestone 29. sij
Odgovor korisniku/ci @AdamMarblestone
Also this is my childhood dog, finally explaining why the Doge meme triggered such a profound response in me
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Adam Marblestone 29. sij
Rare non-science tweet due to recent archival discovery: Photographic evidence strongly suggests my personality development peaked around age 11, and has slowly declined since. Note my offering the cat an entire McDonalds hamburger and putting the rat in my bro’ hat.
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Adam Marblestone 29. sij
Odgovor korisniku/ci @jehosafet
Same!
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Adam Marblestone 29. sij
This paper is so insightful. Surprised how much mileage they could gain out of such a simple setting.
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Michael Cohen 29. sij
VERY important paper from Logothetis' group just posted on about decoding consciousness in PFC in monkeys during a no-report paradigm. VERY critical data for current debates in awareness.
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Aidan Rocke 29. sij
'Using NEURON for Reaction-Diffusion Modeling of Extracellular Dynamics' // 'Development of credible clinically-relevant brain simulations has been slowed due to a focus on electrophysiology...neglecting multi-scale whole-tissue modelling...'
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Greg Jefferis 29. sij
, a : At least since Francis Crick’s famous review of 1979, neuroscientists have dreamed of ways to identify all the neurons connected to a cell of interest. In the last decade this has become a reality through the widespread use of rabies virus tracers. 1/11
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Trenton Bricken 29. sij
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Quoc Le 28. sij
New paper: Towards a Human-like Open-Domain Chatbot. Key takeaways: 1. "Perplexity is all a chatbot needs" ;) 2. We're getting closer to a high-quality chatbot that can chat about anything Paper: Blog:
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summerfieldlab 29. sij
Today I will be teaching my undergrad course "How to build a brain from scratch" for the 2nd year running. I've put the materials online - include a document with all lecture slides and notes, which is about as long as a decent novel. Enjoy!
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Jaan Aru 29. sij
Predictive Routing: "There are no special error-detection circuits or mechanisms." There are instead pathways that are gated by predictions and thus can be activated by unexpected inputs. Amazing monkey electrophysiology work by Andre Bastos
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Alex Naka 28. sij
this is a neat idea - DIY neuropeptide signaling HySyn: A genetically-encoded synthetic synapse to rewire neural circuits in vivo
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Aaron McKethan 27. sij
Epic's call to block a proposed data rule is wrong for many reasons, by and ⁦⁩ in ⁦
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Nature Biotechnology 27. sij
CAR-T cells for solid tumors: there's a new target, Claudin-6. And combination with an RNA vaccine delivering Claudin-6 to immune cells boosts their function in mouse models of cancer
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Philip Ball 23. sij
This paper on the lab culturing of "the closest living relatives of the ancient archaeal host cells from which eukaryotes are thought to have evolved" is pretty fab. These seem like rather weird cells.
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