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ice9
I do quantitative things. Sometimes I think about society and economics.
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ice9 retweeted
Christophe Barraud🛢 5h
Replying to @C_Barraud
🇫🇷 Q3 PRELIMINARY GDP Q/Q: 18.2%❗ V 15.0%E; Y/Y: -4.3% V -7.3%E *Link:
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ice9 retweeted
Christophe Barraud🛢 23h
Replying to @C_Barraud
🇺🇸 U.S. Economy Expands at Record 33.1% Pace After Plunge - Bloomberg
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ice9 5h
Replying to @XHNews
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ice9 16h
Genes with variants associated with severe COVID-19: CCR9 - CCL25 receptor, T cell maturation SLC6A20 - kidney function, details unclear CXCR6 - CD186 receptor, T cell activation LZTFL1 - lung cilia FYCO1 - autophagic vesicle transport IFNAR2 - interferon α/β receptor
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ice9 9h
Replying to @monarchdiaries
The Emperor of All Maladies.
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ice9 9h
Replying to @my_lungs
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ice9 9h
Replying to @Applied_Ion
This is still progress.
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ice9 9h
Replying to @Applied_Ion
Sounds like a leak or a short or both -- frustrating.
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ice9 10h
Replying to @abledoc @NG20194
Fair enough.
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ice9 10h
Replying to @GSharadaa
Antifibrotic agent, mostly via interfering with relevant growth factors. Not sure what kind of effect size to expect. Likely only relevant in severe cases.
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ice9 10h
Replying to @ProvidenceAve
Hypoalbuminemia predisposes to edema-- very unhelpful given pulmonary edema is already a concern. Apart from that, yes, it also leads to hyperlipidemia. Anyway, it often occurs as an indirect result of severe inflammation. Just part of the process.
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ice9 10h
Replying to @abledoc @NG20194
This does not appear to be a translational study. Not sure what you mean by a trial. It's inherently observational-- one cannot assign a genotype (at least, for humans).
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ice9 10h
Replying to @farid__jalali
5-HT2B antagonists: Sarpogrelate Terguride (but also dopamine agonist) Cyproheptadine (also H1 antagonist) Pimethixene (very sim. to cyproheptadine) All also 5-HT2A antagonists.
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ice9 retweeted
Farid Jalali MD 11h
What was that 5HT drug that reduced remodeling?
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ice9 10h
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ice9 10h
Replying to @farid__jalali
5-HT2B antagonists: Sarpogrelate Terguride (but also dopamine agonist) Cyproheptadine (also H1 antagonist) Pimethixene (very sim. to cyproheptadine) All also 5-HT2A antagonists.
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ice9 10h
Replying to @ProvidenceAve
Reasonable indicator. One of many known. Treatment with antiplatelet drugs, antioxidants, inhibitors of NETosis, etc. addresses the processes described.
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ice9 11h
Small sample. Wonder whether the difference was significant.
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ice9 11h
Yes, I agree.
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ice9 16h
Several dozen more reported cases of pulmonary fibrosis to varying degrees, including in some moderate cases.
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