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I’m very happy to post my first #tweeprint about a new manuscript we’ve just put on @biorxivpreprint:
biorxiv.org/content/10.110…
This is work by Ben Cowley, part of his thesis jointly with Byron Yu’s group and my own (Ben is now a postdoc with @jpillowtime). /1 pic.twitter.com/MytfTTQCzn
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SmithLab
@SmithLabNeuro
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13. sij |
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Ben leveraged our large-scale electrophysiological recordings in visual and prefrontal cortex to identify a key signal underlying perceptual decisions. /2
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SmithLab
@SmithLabNeuro
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13. sij |
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This signal, which Ben called “slow drift”, could be described as a neural correlate of impulsivity or arousal. It was tightly related to slow fluctuations in the animal’s behavior in terms of hit rate, false alarm rate, reaction time, and pupil size. /3 pic.twitter.com/211Zn1HE0o
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SmithLab
@SmithLabNeuro
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13. sij |
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Slow drift was present in both visual cortex (V4) and prefrontal cortex (8Ar). These brain areas, centimeters apart, were tightly locked together to this common process. /4
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SmithLab
@SmithLabNeuro
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13. sij |
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Slow drift was weakly present in the population average, but strongly evident in mixtures of simultaneously recorded neurons./5
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SmithLab
@SmithLabNeuro
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13. sij |
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We think this work connects to and substantial advances a rich history of single-neuron studies in non-human primate perceptual decision-making, and provides an important link to numerous recent studies in rodents showing large-scale population activity modulation. /6
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SmithLab
@SmithLabNeuro
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13. sij |
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We hope you enjoy reading the work as much as we enjoyed doing the science, and we'd be happy to hear your thoughts. /7
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