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Nature Biotechnology
CAR-T cells for solid tumors: there's a new target, Claudin-6. And combination with an RNA vaccine delivering Claudin-6 to immune cells boosts their function in mouse models of cancer
Chimeric antigen receptor (CAR)–T cells have been clinically effective in killing certain hematological malignancies, but achieving long-term patient responses for solid tumors remains a challenge....
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