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James A. Ramirez
Dermatopathologist at CTAlab. Digital dermpath. Very curious. Tweets are my own and not medical advice.
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James A. Ramirez retweeted
Silvija Gottesman MD 7 Jun 18
Primary rhabdoid/plasmacytoid melanoma. Amelanotic clinically. Bizzare eccentric nuclei, large nucleoli, abundant pink cytoplasm. Nested or dyscohesive cells. Melan-A stain (cytoplasmic). Behavior like conventional melanoma.
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Christine J. Ko, MD May 2
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Joseph Susa, DO Apr 27
Granular Parakeratosis. Most frequent location is axillary but this case was inframammary. Other sites can include goin, and anogenital. May be related to irritant reaction. The granules are from impaired degradation of keratohyaline granules.
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Lorand Kis Apr 28
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Nicole D. Riddle, MD Mar 20
Perfect section 😍
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James A. Ramirez Apr 29
Extramammary Paget’s disease: groin; good contrast between the p63 (nuclear marker highlighting the normal epidermal cells) and CK7 (marking the malignant cells)
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DermpathJC Apr 20
Stay home, stay safe and join us for a virtual journal club about carcinosarcomas on April 30th, 9pm EST. Temporary open access from . THANK YOU! Link:
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Karen Pinto DNB, FRCPath Apr 14
Melanoma in situ of lentigo maligna type Today’s lecture with Dr. Scott Binder
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Sara Shalin Apr 16
Flowering dogwood tree or talc or starch crystals under polarized light? You tell me. 😊
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Amrit Singh, MD Apr 14
Clefting of the epidermis and clinging of atypical melanocytes to the stripped off epidermis are clues to MIS of lentigo maligna type.
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James A. Ramirez Apr 14
Leiomyoma with beautiful fascicles, some in cross section and some longitudinal. Note bright eosinophilic cytoplasm and cigar-shaped nuclei
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Sara Shalin Apr 7
Daily dose of Stay safe everyone, and
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Jose Candido Apr 13
Sclerosing perineurioma: young patient, acral skin, superficial dermal location. Well-circumscribed spindle cell lesion. EMA+. negative markers (S100, aml, cd34, desmina, bcatenin).
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SocforHemepath Apr 10
For more great review of cutaneous , please also check out Dr. Alejandro Gru's second video: "Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-cell Lymphoma" with open access on our new website!
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Abdullah Alswied Apr 13
🔅Circumscribed Acral Hypokeratosis🔅 ✅Depressed erythematous patches on palms or soles ✅Punched-out thinning of stratum corneum ✅Dilated dermal capillaries 🛑Top DDX: palmoplantar porokeratosis: stratum corneum unremarkable between cornoid lamellae
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Jerad Gardner, MD Apr 4
Eyelid. Primary cutaneous mucinous carcinoma. Islands of basaloid cells in sea of mucin. Indolent. more info in my book:
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Jerad Gardner, MD Apr 8
Now THAT is an atypical mitosis (in ) General rule: pleomorphism & atypical mitoses = aneuploidy (multiple chromosome gains/losses). Translocation driven tumors usually lack these features. Pathology
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Adam J Perricone, MD PhD Apr 8
Replying to @kis_lorand
Was also thinking BFH/DF and looks like there’s some follicular induction. It’s also interesting that solar elastosis vanishes above the lesion
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Henry YANG Apr 1
Beautiful syringoma to enlighten your day! look at those "tadpoles", "commas" all over the place.
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Jerad Gardner, MD Apr 5
Gorgeous Asteroid bodies! I love these little star shaped clusters of degenerated collagen fibers trapped inside histiocytes. A classic buzzword for sarcoidosis, but I see them far more often in foreign body granulomas
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