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@EricTopol | |||||
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There's "precision medicine" and "rabbit hole medicine"
This report represents the latter. How to collect an avg $8,000/person, do many tests to get lots of abnormal findings (for more testing) and "health outcome and benefits were not measured" pnas.org/content/early/… @PNASNews pic.twitter.com/VF6ZMpfarT
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Eric Topol
@EricTopol
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30. sij |
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My colleague @evanmuse and I wrote about this @TheLancet recently thelancet.com/pdfs/journals/…
"High-dimensional data for a human being is an alluring
yet unproven concept; "there is no validation..in the clinic"
@ScrippsRTI @scrippsresearch pic.twitter.com/aav830SaoS
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Eric Topol
@EricTopol
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30. sij |
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Here's the previous report from the same group on "precision medicine" which I label (IMO more precisely) "rabbit-hole medicine." Of 209 people, >33% underwent additional medical imaging due to incidental findings pnas.org/content/pnas/1…
@PNASNews pic.twitter.com/pl23nE406a
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Eric Topol
@EricTopol
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30. sij |
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On deep phenotyping by @segal_eran @WeizmannScience in @NatureOutlook
nature.com/articles/d4158…
"The type and depth of the data collected should be relevant to the disease being studied." pic.twitter.com/zk9Udx3LRm
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*christina
@_Superbrat_
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30. sij |
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They diagnosed someone with renal cell carcinoma from that, who otherwise would have went undetected?
Worth it.
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Eric Topol
@EricTopol
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30. sij |
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There are no data to indicate that diagnosing renal cancer by screening changes outcome.
sciencebasedmedicine.org/54199-2/ pic.twitter.com/iYHB4eUGDr
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Daniel J Drucker
@DanielJDrucker
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30. sij |
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Former unicorn genetics startup Human Longevity loses its horn medcitynews.com/2018/12/former…
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Anthony Letai MD PhD
@DrTonyLetai
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30. sij |
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Just gotta hook that up to AI and it’ll be fine.
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Sumit Middha
@bioinfosm
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30. sij |
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Using exome sequencing at @MayoClinic 5 years ago, we observed and published caution than hype!
mayoclinic.pure.elsevier.com/en/publication… pic.twitter.com/DQLsL8HK5h
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Miletus
@klass1klass2
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30. sij |
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Thank you Dr Topol for putting some sanity in the hype runaway train. Our healthcare costs are unsustainable. Past time for some reality checks.
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Jung Hoon Son, M.D.
@junghoon_sonMD
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30. sij |
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Want to see a plain old family medical history. Likely covers most of the diseases.
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