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Elliot Smith
research faculty studying human neurons, epilepsy, and neural prostheses; also musician. He/him.
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bioRxiv Neuroscience 17 h
Time cells in the human hippocampus and entorhinal cortex support episodic memory
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Stanford Neurosurgery 3. velj
Last week and team performed the first responsive deep brain stimulation (DBS) for obesity in the world! This is the first of 6 planned surgeries for severe funded by and approved.
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Utah Diné Bikéyah 2. velj
“We are not mascots. We are not fallen noble savages. Native Americans pass through airports. We serve in Congress. We take a stand against environmental destruction and cultural eradication. We fight for our children to stay within tribal communities.
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Elliot Smith 31. sij
Odgovor korisniku/ci @mnitabach
I don’t know you, but think you’re hilarious!
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Elliot Smith 29. sij
Seems like we have more days in the red though, non?
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U of U Neurosciences 23. sij
Congratulations to Dr. John Rolston, , and the entire epilepsy team ! Last week, they were the first in the world to use a mini-robot to place a closed-loop stimulator in a patient who suffers from epilepsy.
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Urgyen 23. sij
So my uncle Wangchuk is a traditional Tibetan artist and he made this Tibetan thangka version of the cat meme.
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Bruno Averbeck 22. sij
Our paper supporting a theory first put forth in 1994 by Zohary et al. That suggested that correlations could limit information in large neural populations. Information limiting correlations in large neural populations
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Elliot Smith 23. sij
Odgovor korisniku/ci @yolayne @CUEngineering @CUBoulder
Cool photos!
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Elliot Smith 21. sij
I am a Great Blue Heron! "What bird are you most like?"
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Ed Merricks 🧠 17. sij
Odgovor korisniku/ci @edmerix
Turns out, action potentials in neurons that are recruited to the seizure become shorter in amplitude, and longer in duration (above), and that this is exclusive to the "core" of the seizure (anterior cingulate here). Check out the paper for full gif explanations... !
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Elliot Smith 19. sij
Action potential gifs. ‘Nuff said. Check it out!
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Ed Merricks 🧠 17. sij
New showing the effects of epileptic seizures on individual human neurons, and what this means for our understanding of where seizures are actually happening:
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Misha Tsodyks 13. sij
Our free recall paper is finally out. Phys. Rev. Lett. 124, 018101 (2020) - Fundamental Law of Memory Recall
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Liset M de la Prida 13. sij
Very interesting! Microelectrode recordings are critical for such a fine scale analysis.
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Elliot Smith 13. sij
Odgovor korisniku/ci @50kDinar
These results further emphasize the importance of examining the high frequency LFP spectrum to contextualize seizure recordings in epilepsy research and point to broadband high frequency LFP's utility for understanding seizure mechanisms in the clinical setting.
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Elliot Smith 13. sij
Odgovor korisniku/ci @LMPrida
These analyses were inspired by work from 's lab and further confirm that broadening of the high frequency LFP spectrum is associated with increased population neuronal firing under an electrode, even if that electrode may not be able to record action potentials.
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Elliot Smith 13. sij
Odgovor korisniku/ci @50kDinar
Finally, back to that narrowband gamma, we show that action potentials measured on the microelectrode arrays differentially couple to narrowband gamma before and after the neuronal signature of recruitment into a seizure.
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Elliot Smith 13. sij
Odgovor korisniku/ci @50kDinar
We show this spectral broadening associated with seizing brain tissue can be clearly observed in the spectrum, or measured for each discharge in a seizure using information theoretic quantities.
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Elliot Smith 13. sij
Odgovor korisniku/ci @50kDinar
Note the clear narrowband gamma peak in the above spectrogram, and the increased broadband high frequency LFP after about 40 seconds. The narrowband gamma doesn't distinguish seizing brain tissue, but the broadening of the spectrum in later discharges does.
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